Methods: samples of sputum were collected...

Background: Pulmonary infection in cystic fibrosis (CF) is polymicrobial and it is possible that anaerobic bacteria were not found

routine methods for aerobic culture, living in infected anaerobic airway mucus. Objectives: To determine anaerobic bacteria present in sputum of patients with CF. Methods: Samples of sputum were collected clinically stable adults with CF bronchoalveolar lavage fluid and (BAL) samples

children with CF. Induced sputum samples were taken from healthy volunteers who do not have CF. All samples were processed using

anaerobic bacteriological methods and bacteria in the samples and determined quantitatively. Measurements and Main Results: Anaerobic species primarily in the genera Prevotella,

Veillonella, Propionibacterium

and

Actinomyces were strattera 25mg isolated in large numbers from 42 to 66 (64%) sputum samples of adult patients with CF. Colonization with Pseudomonas

sticks significantly increased the likelihood that anaerobic bacteria are present in sputum. Similar types of anaerobic

were found in BAL of pediatric patients with CF. Although anaerobes were found in induced sputum samples from 16

20 volunteers, they were in much smaller quantities and are usually of different species than those found in the sputum

CF. Type depends on differences in susceptibility to antibiotics with known activity of anaerobes to anaerobes

obvious to all isolates were susceptible to meropenem. Conclusion: The number of anaerobic species are present in large numbers in the lungs of patients with CF. If these anaerobic bacteria

make a significant contribution to infection and inflammation in the lungs in CF, announced changes to antibiotic treatment >> << target anaerobes, in addition to the infection of pathogens may improve control. .